2024
Luong CT, Audira G, Kurnia KA, Hung CH*, Hsiao CD*. Fish 3D locomotion APP (F3LA): a user-friendly computer application package for automatic data calculation and endpoint extraction for novel tank behavior in fish. Journal of Fish Biology (In press)
Kurnia KA, Saputra F, Luong CT, Roldan MJM, Cheng TS*, Hsiao CD*. Performance Comparison for Five Methods Available in ImageJ for Bird Counting and Detection from Video Datasets. Inventions (In press)
Siregar P, Hsieh YC, Audira G, Suryanto ME, Macabeo AP, Vasquez RD, Hsiao CD*. Toxicity Evaluation of Neonicotinoids to Earthworm (Eisenia fetida) Behaviors by a Novel Locomotion Tracking Assay. Environmental Pollution (In press)
Chen HC, Feng WW, Audira G, Kurnia KA, Hung SH, Castillo AL, Roldan MJM, Hsiao CD*, Hung CH*. Evaluation of Sub-Chronic Toxicity of Melamine via Systematic or Oral Delivery in Adult Zebrafish Based on Behavioral Endpoints. Neurotoxicology (In press)
Audira G, Lee JS, Vasquez RD, Roldan MJM, Lai YH, Hsiao CD*. Assessments of Carbon Nanotubes Toxicities in Zebrafish larvae using Multiple Physiological and Molecular Endpoints. Chemico-Biological Interactions (In press)
Siregar P, L YS, Casuga FP, Huang CY, Chen KHC, Huang JC, Hung CH, Lin YK*, Hsiao CD*, Lin HY*. Optimization of Laser-Based Method to Conduct Skin Ablation in Zebrafish and Development of Deep Learning-Based Method for Skin Wound-Size Measurement. Inventions (In press)
Feng WW, Chen HC, Audira G, Suryanto ME, Saputra F, Kurnia KA, Vasquez RD, Casuga FP, Lai YH, Hsiao CD*, Hung CH*. Evaluation of Tacrolimus’ Adverse Effects on Zebrafish in Larval and Adult Stages by Using Multiple Physiological and Behavioral Endpoints. Biology 13(2): 112.
2023
Luong CT, Farhan A, Vasquez RD, Roldan MJM, Lin YK, Hsu SY, Lin MD, Hsiao CD*, Hung CH*. SpiderID_APP: A User-Friendly APP for Spider Identification in Taiwan Using YOLO-Based Deep Learning Models. Inventions. 2023; 8(6):153.
Chang WC, Chen MJ, Hsiao CD, Hu RZ, Huang YS, Chen YF, Yang TH, Tsai GY, Chou CW, Chen RS, Chuang YJ, Liu YW*. The anti-platelet drug cilostazol enhances heart rate and interrenal steroidogenesis and exerts a scant effect on innate immune responses in zebrafish. Plos One 18(10): e0292858.
Audira G, Huang JC, Chen KHC, Kurnia KA, Vasquez RD, Roldan MJM, Lai YH, Hsiao CD*, Yen CY*. A Comprehensive Painkillers Screening by Assessing Zebrafish Behaviors after Caudal Fin Amputation. Biomedicine & Pharmacotherapy 168, 115641.
Suryanto ME, Audira G, Roldan MJM, Lai HT, Hsiao CD*. Color Perspectives in Aquatic Explorations: Unveiling Innate Color Preferences and Psychoactive Responses in Freshwater Crayfish. Toxics 11, 838.
Suryanto ME, Luong CT, Vasquez RD, Roldan MJM, Hung CH, Ger TR*, Hsiao CD*. Using crayfish behavior assay as a simple and sensitive model to evaluate potential adverse effects of water pollution: emphasis on antidepressants. Ecotoxicology and Environmental Safety 265, 115507.
Saputra F, Suryanto ME, Audira G, Luong CT, Hung CH, Roldan MJM, Vasquez RD, Hsiao CD*. Using DeepLabCut for markerless cardiac physiology and toxicity estimation in water fleas (Daphnia magna). Aquatic Toxicology 263, 106676.
Saputra F, Lai YH, Roldan MJM, Alos HC, Aventurado CA, Vasquez RD*, Hsiao CD*. Effect of Pyrethroid Pesticide Fenpropathrin on the Cardiac Performance of Zebrafish and the Potential Mechanism of Toxicity. Biology 12,1214.
Kurnia KA, Lin YT, Farhan A, Malhotra N, Luong CT, Hung CH, Roldan MJM, Tsao CC, Cheng TS*, Hsiao CD* . Deep Learning-Based Automatic Duckweed Counting using StarDist and its Application on Measuring Growth Inhibition Potential of Rare Earth Elements as Contaminants of Emerging Concerns. Toxics, 11, 680.
De Leon MP, Wen FL, Paylaga GJ, Wang YT, Roan HY, Wang CH, Hsiao CD, Lin KH*, Chen CH*. Mechanical waves identify the amputation position during wound healing in the amputated zebrafish tailfin. Nature Physics, 1-9.
Balittan JNI, Luo WJ, Su YW, Yu CY, Wu TY, Chang CA, Jia HW, Lin SR, Hsiao CD*, Yeh JM*. Healing Wounds Efficiently with Biomimetic Soft Matter: Injectable Self-Healing Neutral Glycol Chitosan/Dibenzaldehyde-Terminated Poly (ethylene glycol) Hydrogel with Inherent Antibacterial Properties. ACS Applied Bio Materials 6: 552-565.
2022
Audira G, Hsu TW, Chen KHC, Huang JC, Lin MD*, Ger TR*, Hsiao CD*. A Fast and Cost-Effective (FACE) Instrument Setting to Construct Focus-Extended Images. Inventions 7, 110.
Siregar P, Audira G, Castillo AL, Roldand MJM, Suryanto ME, Liu RX, Lin YT*, Lai YH*, Hsiao CD*. Comparison of the psychoactive activity of four primary Areca nut alkaloids in zebrafish by behavioral approach and molecular docking. Biomedicine & Pharmacotherapy 155, 113809.
Farhan A, Saputra F, Suryanto ME, Humayun F, Pajimna RMB, Vasquez RD, Roldan MJM, Audira G, Lai HT, Lai YH*, Hsiao CD*. OpenBloodFlow: A User-Friendly OpenCV-based Software Package for Blood Flow Velocity and Blood Cell Count Measurement for Fish Embryos. Biology 11, 1471.
Lin HC, Saputra F, Audira G, Lai YH, Roldan MJM, Alos HC, Aventurado CA, Vasquez RD, Tsai GJ, Lim KH*, Hsiao CD*. Investigating Potential Cardiovascular Toxicity of Two Anti-Leukemia Drugs of Asciminib and Ponatinib in Zebrafish Embryos. Int. J. Mol. Sci. 23, 11711.
Abbas K, Raza A, Vasquez RD, Roldan MJM, Malhotra N, Huang JC, Buenafe OEM, Chen KHC, Liang SS*, Hsiao CD*. Ractopamine at the center of decades-long scientific and legal disputes: A lesson on benefits, safety issues, and conflicts. Biomolecules 12, 1342.
Suryanto ME, Saputra F, Kurnia KA, Vasquez RD, Roldan MJM, Chen KHC, Huang JC, Hsiao CD*. Using DeepLabCut as Real-Time and Markerless Tool for Cardiac Physiology Assessment in Zebrafish. Biology 11, 1243.
Young AYW, Audira G, Saputra F, Alos HC, Aventurado CA, Lai YH, Vasquez RD*, Hsiao CD*, Hung CH*. Toxicity Assessment of an Anti-Cancer Drug of p-Toluene Sulfonamide in Zebrafish Larvae Based on Cardiovascular and Locomotion Activities. Biomolecules 12, 1103.
Suryanto ME, Yang CC, Audira G, Vasquez RD, Roldan MJM, Ger TR*, Hsiao CD*. Evaluation of Locomotion Complexity in Zebrafish After Exposure to Twenty Antibiotics by Fractal Dimension and Entropy Analysis. Antibiotics 11,1059.
Suryanto ME, Vasquez RD, Roldan MJM, Chen KHC, Huang JC, Hsiao CD*, Tsao CC*. Establish a High-Throughput Locomotion Tracking Method for Multiple Assessment in Tetrahymena. Cells. 11, 2326.
Saputra F†, Farhan A†, Suryanto ME, Kurnia KA, Chen KHC, Vasquez RD, Roldan MJM, Huang JC,*, Lin YK*, Hsiao CD*. Automated Cardiac Chamber Size and Cardiac Physiology Measurement in Water Fleas by U-Net and Mask RCNN Convolutional Networks. Animals 12, 1670.
Audira G, Suryanto ME, Chen KHC, Vasquez RD, Roldan MJM, Yang CC, Hsiao CD*, Huang JC*. Acute and Chronic Effects of Fin Amputation on Behavior Performance of Adult Zebrafish in 3D Locomotion Test Assessed with Fractal Dimension and Entropy Analyses and Their Relationship to Fin Regeneration. Biology. 11, 969.
Lin YT, Liu RX, Audira G, Suryanto ME, Roldan MJM, Lee JS*, Ger TR*, Hsiao CD* , Lanthanides Toxicity in Zebrafish Embryos Are Correlated to Their Atomic Number. Toxics. 10, 336
Kurnia KA, Sampurna BP, Audira G, Juniardi S, Vasquez RD, Roldan MJM, Tsao CC*, Hsiao CD*. Performance Comparison of Five Methods for Tetrahymena Number Counting in the Imagej Platform: Assessing the Built-in Tool and Machine Learning-Based Extension. IJMS 23(11), 6009.
Chan KY, Yan CCS, Roan HY, Hsu SC, Tseng TL, Hsiao CD, Hsu CP, Chen CH*. Skin cells undergo asynthetic fission to expand body surfaces in zebrafish. Nature, 605, 119–125.
2021
Duan XY, Ma RJ; Hsiao CD, Jiang ZZ, Zhang LY, Zhang Y*, Liu KC. Tripterygium wilfordii multiglycoside-induced hepatotoxicity via inflammation and apoptosis in zebrafish. Chinese Journal of Natural Medicines 19, 750-757.
Farhan A, Kurnia KA, Saputra F, Chen KHC, Huang JC, Roldan MJM, Lai YH*, Hsiao CD*.
An OpenCV-Based Approach for Automated Cardiac Rhythm Measurement in Zebrafish from Video Datasets. Biomolecules 11(10), 1476.
Wu CL, Lin LF, Hsu HC, Huang LF, Hsiao CD, Chou ML*. Saussurea involucrata (Snow Lotus) ICE1 and ICE2 Orthologues Involved in Regulating Cold Stress Tolerance in Transgenic Arabidopsis. IJMS 22(19), 10850.
Abbas K, Saputra F, Suryanto ME, Lai YH, Huang JC, Yu WH, Chen KHC*, Lin YT*, Hsiao CD*. Evaluation of Effects of Ractopamine on Cardiovascular, Respiratory, and Locomotory Physiology in Animal Model Zebrafish Larvae. Cells 10(9), 2449.
Malhotra N, Chen KHC, Huang JC, Lai HT, Uapipatanakul B, Roldan MJM, Macabeo APG*, Ger TR*, Hsiao CD*. Physiological Effects of Neonicotinoid Insecticides on Non-Target Aquatic Animals—An Updated Review. IJMS 22(17), 9591.
Feng Z, Lin C, Tu L, Su M, Song C, Liu S, Suryanto ME, Hsiao CD*, Li L*. An FDA-approved Drug Screening for Compounds that Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish. Cells 10(8), 2149.
Kurnia KA, Santoso F, Sampurna BP, Audira G, Huang JC, Chen KHC*, Hsiao CD*. TCMacro: A Simple and Robust ImageJ-Based Method for Automated Measurement of Tail Coiling Activity in Zebrafish. Biomolecules 11(8), 1133.
Saputra F, Uapipatanakul B, Lee JS, Hung SM, Huang JC, Pang YC, Muñoz JER, Macabeo APG*, Chen KHC*, Hsiao CD*. Co-treatment of Copper Oxide Nanoparticle and Carbofuran Enhances Cardiotoxicity in Zebrafish Embryos. IJMS 22(15), 8259.
Du ZC, Xia ZS, Zhang MZ, Wei YT, Malhotra N, Saputra F, Audira G, Roldan MJM,
Hsiao CD*, Hao EW*, Hou XT*, Deng JG*. Sub-lethal Camphor Exposure Triggers Oxidative Stress, Cardiotoxicity and Cardiac Physiology Alterations in Zebrafish Embryos. Cardiovascular Toxicology 21, 901–913.
Audira G, Lai YH, Huang JC, Chen KHC, Hsiao CD*. Phenomics Approach to Investigate Behavioral Toxicity of Environmental or Occupational Toxicants in Adult Zebrafish (Danio rerio). Current Protocols in Toxicology e223, Volume 1 (doi: 10.1002/cpz1.223).
Li P, Zhang M, Xie D, Zhang X, Zhang S, Gao F, Wang Y, Hsiao CD, Li X*, Liu K*. Characterization and bioactivities of phospholipids from squid viscera and gonads using ultra-performance liquid chromatography-Q-exactive orbitrap/mass spectrometry-based lipidomics and zebrafish models. Food & Function 12, 7986-7996.
Malhotra N, Audira G, Castillo AL, Siregar P, Ruallo JMS, Roldan MJM, Chen JR, Lee JS*, Ger TR*, Hsiao CD*. An Update Report on the Biosafety and Potential Toxicity of Fullerene-Based Nanomaterials toward Aquatic Animals. Oxidative Medicine and Cellular Longevity (Article ID 7995223)
Saputra F, Lai YH, Fernandez RAT, Macabeo APG, Lai HT*, Huang JC*, Hsiao CD*. Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae. Biology 10(6), 548.
Audira G, Siregar P, Chen KHC, Roldan MJM, Huang JC*, Lai HT*, Hsiao CD*. Interspecies Behavioral Variability of Medaka Fish Assessed by Comparative Phenomics. IJMS 22(11), 5686.
Siregar P, Audira G, Feng LY, Lee JH, Santoso F, Yu WH, Lai YH, Li JH*, Lin YT*, Chen JR, Hsiao CD*. Pharmaceutical Assessment Suggests Locomotion Hyperactivity in Zebrafish Triggered by Arecoline Might be Associated with Multiple Muscarinic Acetylcholine Receptors Activation. Toxins 13(4), 259.
Suryanto ME, Audira G, Uapipatanakul B, Hussain A, Saputra F, Siregar P, Chen KHC*, Hsiao CD*. Antidepressant screening demonstrated non-monotonic responses to amitriptyline, amoxapine, and sertraline in locomotor activity assay in larval zebrafish. Cells 10(4), 738.
Audira G, Lee JS, Siregar P, Malhotra N, Rolden MJM, Huang JC, Chen KHC, Hsu HS, Hsu YC, Ger TR, Hsiao CD*. Comparison of the Chronic Toxicities of Graphene and Graphene Oxide toward Adult Zebrafish by Using Biochemical and Phenomic Approaches. Environmental Pollution. 278, 116907.
Siregar P, Suryanto ME, Chen KHC, Huang JC, Chen HM, Kurnia KA, Santoso F, Hussain A, Bui TNH, Saputra F, Audira G, Roldan MJM, Fernandez RA, Macabeo APG*, Lai HT*, Hsiao CD*. Exploiting the freshwater shrimp Neocaridina denticulata as aquatic invertebrate model to evaluate non-targeted pesticide induced toxicity by investigating physiologic and biochemical parameters. Antioxidants 10(3), 391.
Gao M, Xing C, Jiang X, Xu L, Li P*, Hsiao CD. Highly selective fluorescence detection of Cu2+ based on Schiff base functionalized Periodic Mesoiporous Organosilicas. Luminescence 36: 951-957.
Zhang F, Han L, Wang J, Shu M, Liu K, Zhang Y, Hsiao CD, Tian Q*, He Q*. Clozapine Induced Developmental and Cardiac Toxicity on Zebrafish Embryos by Elevating Oxidative Stress. Cardiovasc Toxicol. 21, 399–409.
Kurnia KA, Saputra F, Roldan MJM, Castillo AL, Huang JC, Chen KHC*, Lai HT*, Hsiao CD*. Measurement of Multiple Cardiac Performance Endpoints in Daphnia and
Zebrafish by Kymograph. Inventions , 6(1), 8.
2020
Wang J, Liu K, Mo C, Oleksandr MH, Zhang Y, Chen JR, Hsiao CD*, Zhu Q*, He Q*. Nano-titanium nitride causes developmental toxicity in zebrafish through oxidative stress. DRUG AND CHEMICAL TOXICOLOGY45: 1660-1669.
Lai YH#, Audira G#, Liang ST, Siregar P, Suryanto ME, Lin HC, Villalobos O, Villaflores OB, Hao E*, Lim KH*, Hsiao CD*. Duplicated dnmt3aa and dnmt3ab DNA Methyltransferase Genes Play Essential and Non-Overlapped Functions on Modulating Behavioral Control in Zebrafish. Genes 11(11), 1322
Robea MA, Jijie R, Nicoara M, Plavan G, Ciobica AS*, Solcan C, Audira G, Hsiao CD*, Strungaru SA*. Vitamin C Attenuates Oxidative Stress and Behavioural Abnormalities Triggered by Fipronil and Pyriproxyfen Insecticide Chronic Exposure on Zebrafish Juvenile. Antioxidants 9(10):944.
Audira G, Nguyen TNA, Bui TNH, Malhotra N, Siregar P, Villalobos O, Villaflores OB, Ger TR, Huang JC, Chen KH*, Hsiao CD*. Evaluation of the Adverse Effects of Chronic Exposure of Donepezil (An Acetylcholinesterase Inhibitor) in Adult Zebrafish by Behavioral and
Biochemical Assessments. Biomolecules 10(9):1340.
Malhotra N, Hsu HS, Liang ST, Roldan MJM, Lee JS*, Ger TR*, Hsiao CD*. An Updated Review of Toxicity Effect of the Rare Earth Elements (REEs) on Aquatic Organisms. Animals 10(9):1663.
Santoso F, Krylov VV, Castillo AL, Saputra F, Chen HM, Lai HT*, Hsiao CD*. Cardiovascular Performance Measurement in Water Fleas by Utilizing High-speed Videography and ImageJ Software and Its Application for Pesticide Toxicity Assessment. Animals 10(9):1587.
Santoso F, Farhan A, Castillo AL, Malhotra N, Saputra F, Kurnia KA, Chen KHC, Huang JC*, Chen JR*, Hsiao CD*. An Overview of Methods for Cardiac Rhythm Detection in Zebrafish. Biomedicines 8(9):329.
Hussain A, Audira G, Malhotra N, Uapipatanakul B, Chen JR, Lai YH, Huang JC, Chen KHC *, Lai HT*, Hsiao CD*. Multiple Screening of Pesticides Toxicity in Zebrafish and Daphnia Based on Locomotor Activity Alterations. Biomolecules 10(9), 1224.
Hsiao CD, Wu HH, Malhotra N, Liu YC, Wu YH, Lin YN, Saputra F, Santoso F, Chen KHC*.
Expression and Purification of Recombinant GHK Tripeptides able to Protect against Acute Cardiotoxicity from Exposure to Waterborne-Copper in Zebrafish. Biomolecules 10(9):1202.
Malhotra N, Villaflores OB, Audira G, Siregar P, Lee JS*, Ger TR*, Hsiao CD*. Toxicity Studies on Graphene-based Nanomaterials in Aquatic Organisms: Current Understanding. Molecules 25(16): 3618.
Siregar P, Juniardi S, Audira G, Lai YH, Huang JC, Chen KHC *, Chen JR*, Hsiao CD*. Method Standardization for Conducting Innate Color Preference Study in Different Zebrafish Strains. Biomedicines 8(8):271.
Audira G, Siregar P, Strungaru SA, Huang JC*, Hsiao CD*. Which Zebrafish Strains Are More Suitable to Perform Behavioral Studies ? A Comprehensive Comparison by Phenomic Approach. Biology 9(8):200.
Audira G, Siregar P, Chen JR, Lai YH, Huang JC, Hsiao CD*. Systematical Exploration of the Common Solvent Toxicity at Whole Organism Level by Behavioral Phenomics in Adult Zebrafish. Enviornmental Pollution. 266: 115239.
Malhotra N, Lee JS, Liman RAD, Ruallo JMS, Villaflores OB, Ger TR*, Hsiao CD*. Potential Toxicity of Iron Oxide Magnetic Nanoparticles: A Review. Molecules 25(14), 3159.
Chen RY, Bui TNH, Audira G, Lou B*, Lin MD*, Hsiao CD*. Meta-transcriptomic Analysis of RNAseq Data Reveals Pacu and Loach Fish with Unusually High Levels of Myoglobin Expression in Skeletal Muscles. Animals 10, 1130.
Hussain A, Audira G, Siregar P, Lin YC, Villalobos O, Villaflores O, Wang WD*, Hsiao CD*. Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish. International Journal of Environmental Research and Public Health 17, 4632.
Chen RY, Lin CJ, Liang ST, Villalobos O, Villaflores O, Lou B*, Lai YH*, Hsiao CD*. UVB Irradiation Induced Cell Damages and Early Onset of Junbb Expression in Zebrafish. Animals 10, 1096.
Balitaan JNI, Hsiao CD, Yeh JM, Santiago KS*. Innovation inspired by nature: Biocompatible self-healing injectable hydrogels based on modified-β-chitin for wound healing. International Journal of Biological Macromolecules. 162, 723-736.
Malhotra N, Ger TR, Uapipatanakul B, Huang JC, Chen KHC*, Hsiao CD*. Review of Copper and Copper Nanoparticle Toxicity in Fish. Nanomaterials 10,1126.
Malhotra N, Audira G, Chen JR, Siregar P, Hsu HS, Lee JS*, Ger TR*, Hsiao CD*. Surface Modification of Magnetic Nanoparticles by Carbon-Coating Can Increase its Biosafety: Evidences from Biochemical and Neurobehavioral Tests in Zebrafish. Molecules 25(9), 2256
Lin YN, Audira G, Malhotra N, Nguyen TNA, Siregar P, Lu JH, Lee H*, Hsiao CD*. A Novel Function of the Lysophosphatidic Acid Receptor 3 (LPAR3) Gene in Zebrafish on Modulating Anxiety, Circadian Rhythm Locomotor Activity, and Short-Term Memory. Int. J. Mol. Sci. 21, 2837.
Bui TNH, Nguyen TNA, Audira G, Siregar P, Liang ST, Huang JC*, Hsiao CD*. Chronic Exposure to Low Concentration Lead Chloride Induced Anxiety and Loss of Aggression and Memory in Zebrafish. Int. J. Mol. Sci. 21, 1844.
Bui TNH, Nguyen TNA, Audira G, Juniardi S, Liman R, Villaflores O, Lai YH, Chen JR, Liang ST, Huang JC*, Hsiao CD*. Development of a Modified Three-Day T-maze Protocol for Evaluating Learning and Memory Capacity of Adult Zebrafish. Int. J. Mol. Sci. 21, 1464.
Sarasamma S, Audira G, Siregar P, Malhotra N, Lai YH, Liang ST, Chen JR*, Chen KHC*, Hsiao CD*. Nanoplastics Cause Neurobehavioral Impairments, Reproductive and Oxidative Damages, and Biomarker Responses in Zebrafish: Throwing up Alarms of Wide Spread Health Risk of Exposure. Int. J. Mol. Sci. 21, 1410.
Li X, Li C, Zhu Y, Shi Y, Zhang X, Zhang S, Wang L, Lin H, Hou H, Hsiao CD, Han L, Liu K*. Lipid Fingerprinting of Different Material Sources by UPLC-Q-Exactive Orbitrap /MS Approach and Their Zebrafish-Based Activities Comparison. J Agric Food Chem. 68: 2007-2015.
2019
Song Z, Zhang Y, Zhang H, Rajendran RS, Wang R, Hsiao CD, Li J, Xia Q, Liu K*. Isoliquiritigenin triggers developmental toxicity and oxidative stress-mediated apoptosis in zebrafish embryos/larvae via Nrf2-HO1/JNK-ERK/mitochondrion pathway.
Chemosphere. 246:125727.
Zhang X, Shi Y, Wang L, Li X, Zhang S, Wang X, Jin M, Hsiao CD, Lin H, Han L, Liu K*. Metabolomics for Biomarker Discovery in Fermented Black Garlic and Potential Bioprotective Responses against Cardiovascular Diseases. J Agric Food Chem. 67(44):12191-12198.
Sarasamma S, Audira G, Samikannu P, Juniardi S, Siregar P, Hao E*, Chen JR*, Hsiao CD*. Behavioral Impairments and Oxidative Stress in the Brain, Muscle, and Gill Caused by Chronic Exposure of C70 Nanoparticle on Adult Zebrafish. Int. J. Mol. Sci. 20, 5795
Santoso F, Sampurna BP, Lai YH, Liang ST, Hao E*, Chen JR*, Hsiao CD*. Development of a Simple ImageJ-based Method for Dynamic Blood Flow Tracking in Zebrafish Embryos and Its Application in Drug Toxicity Evaluation. Inventions 4(4):65
Du Z, Fanshi F, Lai YH, Chen JR, Hao E*, Deng J*, Hsiao CD*. Mechanism of anti-dementia Effects of Mangiferin in a Senescence Accelerated Mouse (SAMP8) Model. Bioscience Reports 39 (9): BSR20190488
Huo J, Yu Q, Zhang Y, Liu K, Hsiao CD, Jiang Z*, Zhang L*. Triptolide‐induced hepatotoxicity via apoptosis and autophagy in zebrafish. J Appl Toxicol. 39: 1532-1540.
Liang ST, Chen JR, Tsai JJ, Lai YH*, Hsiao CD*. Overexpression of Notch Signaling Induces Hyperosteogeny in Zebrafish. IJMS, 20(15), 3613
Sampurna BP, Santoso F, Lee JH, Yu WH, Wu CC, Audira G, Juniardi S, Chen JR, Lin YT* , Hsiao CD*. Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish. Cells, 8(6), 566
Malhotra N, Chen JR, Sarasamma S, Audira G, Siregar P, Liang ST, Lai YH, Lin GM*, Ger TR*, Hsiao CD*. Ecotoxicity Assessment of Fe3O4 Magnetic Nanoparticle Exposure in Adult Zebrafish at Environmental Pertinent Concentration by Behavioral and Biochemical Testing. Nanomaterials, 9(6), 873
Audira G, Sampurna BP, Juniardi S, Laing ST, Lai YH, Han L*, Hsiao CD*. Establishing Simple Image-based Methods and Cost-effective Instrument for Toxicity Assessment on Circadian Rhythm Dysregulation in Fish. Biology Open 8: bio041871
Liang ST, Audira G, Juniardi S, Chen JR, Lai YH, Du ZC*, Lin DS*, Hsiao CD*. Zebrafish Carrying pycr1 Gene Deficiency Display Aging and Multiple Behavioral Abnormalities. Cells, 8, 453.
Jia ZL, Cen J, Wang JB, Zhang F, Xia Q, Wang X, Chen XQ, Wang RC, Hsiao CD,
Liu KC, Zhang Y*. Mechanism of isoniazid-induced hepatotoxicity in zebrafish
larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway.
Chemosphere. 227:541-550.
Zhang Y, Cen J, Jia Z, Hsiao CD, Xia Q, Wang X, Chen X, Wang R, Jiang Z, Zhang
L, Liu K*. Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through
Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish.
Antimicrob Agents Chemother. 63(5). pii: e01639-18.
Hao E, Pang G, Du Z, Lai YH, Chen JR, Xie J, Zhou K, Hou X*, Hsiao CD*, Deng J*. Peach Kernel Oil Downregulates Expression of Tissue Factor and Reduces Atherosclerosis in ApoE knockout Mice. Int. J. Mol. Sci. 20, 405.
Jin M, Xiao Z, Zhang S, Men X, Li X, Zhang B, Zhou T, Hsiao CD, Liu K*. Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos. Chemosphere 219:557-566.
2018
Audira G, Sarasamma S, Chen JR, Juniardi S, Sampurna BP, Liang ST, Lai YH, Lin GM*, Hsieh MC*, Hsiao CD*. Zebrafish Mutants Carrying leptin a (lepa) Gene deficiency display obesity, anxiety, less aggression and fear, circadian rhythm and color preference dysregulation. IJMS 19, 4038
Sarasamma S, YH Lai, ST Liang, K Liu*, Hsiao CD*. The power of fish models to elucidate skin cancer pathogenesis and impact on the discovery of new therapeutic opportunities. IJMS 19, 3929
Sarasamma S, Audira G, Juniardi S, Sampurna BP, YH Lai, E Hao*, JR Chen*, Hsiao CD*.
Evaluation of the Effects of Carbon 60 Nanoparticle Exposure to Adult Zebrafish: A Behavioral and Biochemical Approach to Elucidate the Mechanism of Toxicity. IJMS 19, 3853
Audira G, Sampurna BP, Juniardi S, Liang ST, Lai YH*, Hsiao CD*. A versatile setup for measuring multiple behavior endpoints in Zebrafish. Inventions 3(4), 75.
Sarasamma S, Audira G, Juniardi S, Sampurna BP, Liang ST, Hao E*, Lai YH*, Hsiao CD*. Zinc chloride exposure inhibits brain acetylcholine level and produces neurotoxic signatures and diminish memory and motor activities in adult zebrafish. IJMS 19, 3195
Xiong X, Liu Y, Shan L, Xu Y, Liang J*, Lai YH *, Hsiao CD*. Evaluation of collagen mixture on promoting skin wound healing in zebrafish caused by acetic acid administration. Biochem. Biophys. Res. Commun. 505(2): 516-522.
Hsieh FC, Lu YF, Liau I, Chen CC, Cheng CM, Hsiao CD, Hwang SL*. Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells. Sci Rep. 8(1):7856.
Chou CH, Huang HY, Huang WC, Hsu SD, Hsiao CD, Liu CY, Chen YH, Liu YC, Huang WY, Lee ML, Chen YC, Huang HD*. The aquatic animals' transcriptome resource for comparative functional analysis. BMC Genomics. 19(Suppl 2):103.
Sampurna BP, Audira G, Juniardi S, Lai YH*, Hsiao CD*. A Simple ImageJ-Based Method to Measure Cardiac Rhythm in Zebrafish Embryos. Inventions, 3(2), 21.
Audira G, Sampurna BP, Juniardi S, Liang ST, Lai YH, Hsiao CD*. A Simple Setup to Perform 3D Locomotion Tracking in Zebrafish by Using a Single Camera. Inventions, 3(1), 11.
Schepis A, Barker A, Srinivasan Y, Balouch E, Zheng Y, Lam I, Clay H, Hsiao CD, Coughlin SR*. Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia. J Cell Biol, jcb-201709118.
2017
Chen JR, Lai YH, Tsai JJ, Hsiao CD*. Live Florescent Staining Platform Drug-Screening and Mechanism-Analysis in Zebrafish for Bone Mineralization. Molecules 22:2068.
Lin GM, Lai YH, Audira G, Hsiao CD*. A simple method to decode the complete 18-5.8-28S rRNA repeated units of green algae by genome skimming. International Journal of Molecular Sciences 18:2341.
Sarasamma S, Varikkodan MM, Liang ST, Lin YC, Wang WP, Hsiao CD*. Zebrafish: A Premier Vertebrate Model for Biomedical Research in Indian Scenario. Zebrafish 14: 589-605.
Lee SC, Hsiao CD, Wang YS, Lou SW*. Transcriptome response of previtellogenic ovary in Anguilla japonica after artificial hormone injection. Mar Genomics 35:31-34.
Zhang H, Audira G, Li Y, Xian W*, Varikkodan MM, Hsiao CD*. Comparative study the expression of calcium cycling genes in Bombay duck (Harpadon nehereus) and beltfish (Trichiurus lepturus) with different swimming activities. Genomics Data. 12: 58-61.
Nie CH, Wan SM, Tomljanovic T, Treer T, Hsiao CD, Wang WM, Gao ZX*. Comparative proteomics analysis of teleost intermuscular bones and ribs provides insight into their development. BMC Genomics. 18: 147.
Xie Q, Shen KN, Hao X, Phan NN, Hieu BT, Chen CH, Zhu C, Lin YC*, Hsiao CD*. The complete chloroplast genome of Tianshan Snow Lotus (Saussurea involucrata), a famous traditional Chinese medicinal plant of the family Asteraceae. Mitochondrial DNA Part A 28: 294-295.
Zhan W, Chen R, Shen KN, Xu D, Hsiao CD*, Lou B*. Next generation sequencing yields the complete mitochondrial genome of the Redbelly yellowtail fusilier, Caesio cuning (Teleostei: Caesionidae). Mitochondrial DNA Part A 28: 125-126.
Xiang P, Lin M, Wang Y, Audira G, Liang ST, Hsiao CD*. The complete mitogenome of sea slug, Nembrotha kubaryana (Mollusca: Polyceridae). Conservation Genet Resour 9: 245-247.
2016
Zhang Y, Han L, He Q, Chen W, Sun C, Wang X, Chen X, Wang R, Hsiao CD, Liu K*. A rapid assessment for predicting drug-induced hepatotoxicity using zebrafish. J Pharmacol Toxicol Methods, 84: 102–110.
Zhang Y, Liu K, Hassan HM, Guo H, Ding P, Han L, He Q, Chen W, Hsiao CD, Zhang L, Jiang Z*. Liver Fatty Acid Binding Protein Deficiency Provokes Oxidative Stress, Inflammation, and Apoptosis-Mediated Hepatotoxicity Induced by Pyrazinamide in Zebrafish Larvae. Antimicrob Agents Chemother 60(12): 7347-7356.
Zhang WZ, Xiong XM, Zhang XJ, Wan SM, Guan NN, Nie CH, Zhao BW, Hsiao CD, Wang W, Gao ZX*. Mitochondrial genome variation after hybridization and differences in the first and second generation hybrids of bream fishes. PLoS One 11: e0158915.
Chen Z, Liu L, Shen KN, Chen CH, Hsiao CD*, Gao TX*. Isolation and characterization of 28 polymorphic microsatellite markers of the Pacific seaweed pipefish Syngnathus schlegeli. Conservation Genet Resour (In press)
Zhang H, Chang CM, Shen KN, Xian W*, Hsiao CD*. Identification of myogenic regulatory genes in the muscle transcriptome of beltfish (Trichiurus lepturus): a major commercial marine fish species with robust swimming ability. Genomics Data 8: 81-84.
Ho CH, Hsiao CD, Kawakami K, Tse KF*. Triclosan (TCS) exposure impairs lipid metabolism in zebrafish embryos. Aquatic Toxicology 173: 29-35.
Xu D, Shen KN, Fan Z, Huang W, You F, Lou B*, Hsiao CD*. The testis and ovary transcriptomes of the rock bream (Oplegnathus fasciatus) : a bony fish with a unique neo Y chromosome. Genomics Data 7: 210-213.
Xu M, Jiang L, Shen KN, Wu C, He G*, Hsiao CD*. Transcriptome response to copper heavy metal stress in hard-shelled mussel (Mytilus coruscus). Genomics Data 7: 152-154.
Lu Z, Liu W, Liu L, Shi H, Ping H, Wang T, Chi C, Wu C, Chen CH, Shen KN*, Hsiao CD*. De novo assembly and comparison of the ovarian transcriptomes of the common Chinese cuttlefish (Sepiella japonica) with different gonadal development. Genomics Data 7: 155-158.
Liu YC, Hsu SD, Chou CH, Huang WY, Chen YH, Liu CY, Lyu GJ, Huang SZ, Aganezov S, Alekseyev M, Hsiao CD*, Huang HD*. Transcriptome sequencing based annotation and homologous evidence based scaffolding of Anguilla japonica draft genome. BMC Genomics 17: S13.
Lin GM, Shen KN, Hsiao CD*. Next generation sequencing yields the complete mitogenome of nereid worm, Namalycastis abiuma (Annelida: Nereididae). Mitochondrial DNA Part B 1: 103-104.
Zhang Y, Guo YM, Li TJ, Chen CH, Shen KN, Hsiao CD*. The complete chloroplast genome of Wakame (Undaria pinnatifida), an important economic macroalga of the family Alariaceae. Mitochondrial DNA Part B 1: 25-26.
Zhang Y, Guo YM, Li TJ, Chen CH, Shen KN, Hsiao CD*. The complete chloroplast genome of Gracilariopsis lemaneiformis, an important economic red alga of the family Gracilariaceae. Mitochondrial DNA Part B 1: 2-3.
Niu W, Lin R, Shi X, Chen CH, Shen KN, Hsiao CD*. Next generation sequencing yields the complete mitogenome of massive coral, Porites lutea (Cnidaria: Poritidae). Mitochondrial DNA Part B 1: 8-9.
Niu W, Huang H, Lin R, Chen CH, Shen KN, Hsiao CD*. The complete mitogenome of the Galaxy Coral, Galaxea fascicularis (Cnidaria: Oculinidae). Mitochondrial DNA Part B 1: 10-11.
Xiang P, Lin M, Zhao L, Shen KN, Hsiao CD*. Low coverage genome sequencing yields the complete mitogenome of Pyjama Slug, Chromodoris quadricolor (Mollusca: Chromodorididae). Mitochondrial DNA Part B 1: 94-95.
Xiang P, Lin M, Wang Y, Shen KN, Hsiao CD*. The complete mitogenome of sea slug, Phyllidia ocellata (Mollusca: Phyllidiidae). Mitochondrial DNA Part B 1: 96-97.
Shen KN, Chang CW, Lin ZH, Chan YF, Tsai SY, Chen CH, Hsiao CD*. Complete mitogenomes of Cocos lemonpeel angelfish (Centropyge flavissima) and Eibl’s angelfish (Centropyge eibli) (Teleostei: Pomacanthidae). Mitochondrial DNA Part A 27: 3709-3710.
Shen KN, Chang CW, Chan YF, Lin ZH, Tsai SY, Chen CH, Hsiao CD*. Complete mitogenomes of Woodhead's angelfish (Centropyge woodheadi) and Herald's angelfish (Centropyge heraldi) (Teleostei: Pomacanthidae). Mitochondrial DNA Part A 27: 3672-3673.
Hsiao CD, Shen KN, Chan YF, Lin ZH, Tsai SY, Chen CH, Chang CW*. Complete mitogenomes of Spotbreast angelfish (Genicanthus melanospilos) and Blackstriped angelfish (Genicanthus lamarck) (Teleostei: Pomacanthidae) . Mitochondrial DNA Part A 27: 2969-2970.
Shen KN, Chang CW, Lin ZH, Chan YF, Tsai SY, Chen CH, Hsiao CD*. Complete mitogenomes of Whitetail angelfish (Centropyge flavicauda) and Orangeback angelfish (Centropyge acanthops) (Teleostei: Pomacanthidae). Mitochondrial DNA Part A 27: 2951-2952.
Shen KN, Chang CW, Tsai SY, Lin ZH, Chan YF, Chen CH, Hsiao CD*. Complete mitogenomes of Barred angelfish (Paracentropyge multifasciata) and Purplemask angelfish(Paracentropyge venusta) (Teleostei: Pomacanthidae) Mitochondrial DNA Part A 27: 2945-2946.
Yao CJ, Chen CH, Hsiao CD*. The complete mitogenome of Ginkgo-toothed beaked whale (Mesoplodon ginkgodens) (Chordata: Ziphiidae). Mitochondrial DNA Part A 27: 2846-2847.
Shen KN, Chang CW, Chen CH, Hsiao CD*. Complete mitogenomes of King angelfish (Holacanthus passer) and Queen angelfish (Holacanthus ciliaris) (Teleostei: Pomacanthidae) Mitochondrial DNA Part A 27: 2815-2816.
Shen KN, Chen CH, Hsiao CD*. Complete mitogenomes of Guinean angelfish (Holacanthus africanus) and Rock beauty (Holacanthus tricolor) (Teleostei: Pomacanthidae)
Mitochondrial DNA Part A 27: 2769-2770.
Shen KN, Chang CW, Chen CH, Hsiao CD*. Complete mitogenomes of Multicolor angelfish (Centropyge multicolor) and Yellowhead angelfish (Centropyge joculator) (Teleostei:Pomacanthidae) Mitochondrial DNA Part A 27: 2807-2808.
Shen KN, Chang CW, Chen CH, Hsiao CD*. Complete mitogenomes of Armitage angelfish(Apolemichthys armitagei) and Griffisi angelfish (Apolemichthys griffisi) (Teleostei:Pomacanthidae) Mitochondrial DNA Part A 27: 2683-2684.
Loh KH, Shao KT, Chen CH, Chen HM, YH Then, Loo PL, Lim PE, Chong VC, Shen KN*,Hsiao CD*. Next generation sequencing yields the complete mitogenome of two moray eels ofGymnothorax formosus and Scuticaria tigrina (Anguilliformes: Muraenidae) Mitochondrial DNA Part A 27: 2651-2652.
Hsiao CD, Shen KN, Tsai SY, Wu SC, Chen CH, Chang CW*. The complete mitogenome of Japanese shallow angelfish (Genicanthus semifasciatus) and Ornate angelfish (Genicanthus bellus) (Teleostei: Pomacanthidae) Mitochondrial DNA Part A 27: 2627-2628.
Shen KN, Chang CW, Tsai SY, Wu SC, Lin ZH, Chan YF, Chen CH, Hsiao CD*, P Borsa. Next generation sequencing yields the complete mitogenome of Leopard whipray (Himantura leoparda) and Blue-spotted stingray (Neotrygon kuhlii) (Chondrichthyes: Dasyatidae) Mitochondrial DNA Part A 27: 2613-2614.
Hsiao CD, Shen KN, Ching TY, Wang YH, Ye JJ, Tsai SY, Wu SC, Chen CH, Wang CH*. The complete mitochondrial genome of the cryptic “lineage A” big-fin reef squid, Sepioteuthis lessoniana (Cephalopoda: Loliginidae) in Indo-West Pacific. Mitochondrial DNA Part A 27: 2433-2434.
Loh KH, Shao KT, Chen HM, Chen CH, Loo PL, Then YH, Lim PE, Chong VC, Shen KN*, Hsiao CD*. Next generation sequencing yields the complete mitochondrial genome of the longfang moray, Enchelynassa canina (Anguilliformes: Muraenidae). Mitochondrial DNA Part A 27: 2431-2432.
Loh KH, Shao KT, Chen HM, Chen CH, Chong VH, Loo PL, Shen KN*, Hsiao CD*. Next generation sequencing yields the complete mitochondrial genome of the Zebra moray,Gymnomuraena zebra (Anguilliformes: Muraenidae). Mitochondrial DNA Part A 27: 2430-2431.
Shen KN, Tsai SY, Chen CH, Hsiao CD*, Durand JD. Next generation sequencing yields the complete mitochondrial genome of the largescale mullet, Liza macrolepis (Teleostei: Mugilidae). Mitochondrial DNA Part A 27: 4232-4233.
Shen KN, Chen CH, Hsiao CD*, Durand JD. Next generation sequencing yields the complete mitochondrial genome of the flathead mullet, Mugil cephalus cryptic species in East Australia (Teleostei: Mugilidae). Mitochondrial DNA Part A 27: 3218-3219.
Shen KN, Chang CW, Chen CH, Hsiao CD* . Next generation sequencing yields the complete mitochondrial genome of the Regal angelfish, Pygoplites diacanthus (Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4149-4150.
Shen KN, Chang CW, Chen CH, Chassaing A, Hsiao CD* . Next generation sequencing yields the complete mitochondrial genome of the Japanese angelfish, Centropyge interrupta(Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4116-4117.
Shen KN, Chang CW, Loh KH, Chen CH, Hsiao CD*. Next generation sequencing yields the complete mitochondrial genome of the Clarion angelfish, Holacanthus clarionensis(Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4118-4119.
Shen KN, Chang CW, Chen CH, Hsiao CD*. The complete mitochondrial genome of the Tiger angelfish, Apolemichthys kingi (Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4120-4121.
Shen KN, Loh KH, Chen CH, Hsiao CD*. The complete mitochondrial genome of the Blue-face angelfish, Pomacanthus xanthometapon (Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4122-4123.
Hsiao CD, Shen KN, Chen CH, Chang CW*. The complete mitochondrial genome of the Vermiculated angelfish (Chaetodontoplus mesoleucus) (Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4124-4125.
Ye JJ, Shen KN, Chen CH, Hsiao CD, Chang CW*. The complete mitochondrial genome of the Emperor angelfish, Pomacanthus imperator (Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 4126-4127.
Shen KN, Chang CW, Chen CH, Hsiao CD*. The complete mitochondrial genome of the Spectacled angelfish, Chaetodontoplus conspicillatus (Perciformes: Pomacanthidae). Mitochondrial DNA Part A 27: 3919-3920.
Shen KN, Chen CH, Hsiao CD*. Next generation sequencing yields the complete mitochondrial genome of the Hornlip mullet, Plicomugil labiosus (Teleostei: Mugilidae). Mitochondrial DNA Part A 27: 2192-2193.
Shen KN, Yen TC, Chen CH, Ye JJ, Hsiao CD*. The complete mitochondrial genome of the cryptic “lineage B” big-fin reef squid, Sepioteuthis lessoniana (Cephalopoda: Loliginidae) in Indo-West Pacific. Mitochondrial DNA Part A 27: 2100-2101.
Shen KN, Yen TC, Chen CH, Li HY, Chen PL, Hsiao CD*. Next generation sequencing yields the complete mitochondrial genome of the flathead mullet, Mugil cephalus cryptic species NWP2 (Teleostei: Mugilidae). Mitochondrial DNA Part A 27: 1758-1759.
2015
Wang X, Liu KC*, Sun GJ, Han LW, Wang RC, Peng WB, Sun C, Hsiao CD, Zhang Y, Hou HR. Evaluation of nephrotoxic effects of aristolochic acid on zebrafish (Danio rerio) larvae. Hum Exp Toxicol 35: 974-982.
Sun G, Liu K*, Wang X, Liu X, He Q, Hsiao CD. Identification and expression analysis of zebrafish (Danio rerio) E-selectin during embryonic development. Molecules 20: 18539-18550.
Lin DS*, Hsiao CD, Lee AY, Ho CS, Liu HL, Wang TJ, Jian YR, Hsu JC, Huang ZD, Lee TH, Chiang MF*. Mitigation of Cerebellar Neuropathy in Globoid Cell Leukodystrophy Mice by AAV-Mediated Gene Therapy. Gene 571: 81-90.
2014
Chang TY, Huang TS, Wang HW, Chang SJ, Lo HH, Chiu YL, Wang YL, Hsiao CD, Tsai CH, Chan CH, You RI, Wu CH, Tsai TN, Cheng SM, Cheng CC*. miRNome traits analysis on endothelial lineage cells discloses biomarker potential circulating microRNAs which affect progenitor activities. BMC Genomics. 15: 802.
Huang SY, Feng CW, Hung HC, Chakraborty C, Chen CH, Chen WF, Jean YH, Wang HM, Sung CS, Sun YM, Wu CY, Liu W, Hsiao CD, Wen ZH*. A novel zebrafish model to provide mechanistic insights into the inflammatory events in carrageenan-induced abdominal edema. PLoS One 9:e104414.
Chen CH, Lin DS, Cheng CW, Lin CJ, Lo YK, Yen CC, Lee YL*, Hsiao CD*. Cdc6 cooperates with c-Myc to promote genome instability and EMT in zebrafish. Oncotarget 5:6300-6311.
Lim KH*, Lin HC, Chen GS, Chiang, YH, Hsiao CD, Kuo YY. CALR Mutations in Myeloproliferative Neoplasms. International Journal of Gerontology 8:105.
Feng CW, Wen ZH, Huang SY, Hung HC, Chen CH, Yang SN, Chen NF, Wang HM, Hsiao CD, Chen WF. Effects of 6-Hydroxydopamine Exposure on Motor Activity and Biochemical Expression in Zebrafish (Danio Rerio) Larvae. Zebrafish 11:227-239.
Yen CC*, Hsiao CD, Chen WM, Wen YS, Lin YC, Chang TW, Yao FY, Hung SC, Wang JY, Chiu JH, Wang HW, Lin CH, Chen TH, Chen PC, Liu CL, Tzeng CH, Fletcher JA. Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition. Oncotarget. 5:716-725.
Lin DS*, Chuang TP, Chiang MF, Ho CS, Hsiao CD, Huang YW, Wu TY, Wu JY, Chen YT, Chen TC, Li LH. De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay. Gene. 533: 78-85.
2013
Chen SY, Shih HY, Lin SJ, Hsiao CD, Li ZC, Cheng YC*. Etv5a regulates the proliferation of ventral mesoderm cells and the formation of hemato-vascular derivatives. J Cell Sci. 126: 5626-5634.
Lin CY, Huang CC, Wang WD, Hsiao CD, Cheng CF, Wu YT, Lu YF, Hwang SP*. Low temperature mitigates cardia bifida in zebrafish embryos. PLoS One. 8:e69788.
Shih DF, Hsiao CD, Min MY, Lai SL, Yang CW, Lee WT*, Lee SJ*. Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor Functions. PLoS One. 8:e71741.
Lin DS*, Chiang MF, Ho CS, Hsiao CD, Lin CY, Wang NL, Chuang CK, Huang YW, Chang PC, Liu HL. Low-frequency enzyme replacement therapy in late-onset pompe disease. Muscle Nerve 47:612-613.
Hsiao CD*. Memorial Article on Chi-Bin Chien. Hereditas (Beijing), 35:519-521. (Invited review article)
2012
Chen CF, Chen CP, Hsiao CD*. Zebrafish research in Taiwan . Hereditas (Beijing). In press. (Invited review article)
Chu CY, Chen CF, Rajendran R. Samuel, Shen CN, Chen TH, Yen CC, Chuang CK, Lin DS, Hsiao CD*. Overexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafish. PLoS One. 7:e36474.
Chen YC, Chen YC, Lin WD, Hsiao CD, Chiu HW, Ho JM*. Bio301: a web-based EST annotation pipeline that facilitates functional comparison studies. ISRN Bioinformatics. 139842.
2011
Huang SH, Hsiao CD, Lin DS, Chow CY, Chang CJ, Liau I*. Imaging of Zebrafish In Vivo with Second-Harmonic Generation Reveals Shortened Sarcomeres Associated with Myopathy Induced by Statin. PLoS One. 6:e24764.
Lin YS, Tsai SC, Lin HC, Hsiao CD, Wu SM*. Changes of glycogen metabolism in the gills and hepatic tissue of tilapia (Oreochromis mossambicus) during short-term Cd exposure. Comp Biochem Physiol C Toxicol Pharmacol. 154:296-304.
Liu DW, Hsu CH,Tsai SM, Hsiao CD, Wang WP*. A Variant of Fibroblast Growth Factor Receptor 2 (Fgfr2) Regulates Left-Right Asymmetry in Zebrafish. PLoS One. 6:e21793.
Chen CF, Chu CY,Chen TH, Lee SJ, Shen CN, Hsiao CD*. Establishment of a transgenic zebrafish line for superficial skin ablation and functional validation of apoptosis modulators in vivo. PLoS One. 6:e20654.
Lin DS*, Hsiao CD, Liau I, Lin SP, Chiang MF, Chuang CK, Wang TJ, Wu TY, Jian YR, Huang SF, Liu HL. CNS-targeted AAV5 gene transfer results in global dispersal of vector and prevention of morphological and function deteriorationin CNS of globoid cell leukodystrophy mouse model. Mol Genet Metab. 103:367-377.
Yeh CM, Liu YC, Chang CJ, Lai SL, Hsiao CD, Lee SJ*. Ptenb mediatesgastrulation cell movements via Cdc42/AKT1 in zebrafish. PLoS One. 6:e18702.
Before 2009
2009. Chang WJ, HorngJL, Yan JJ, Hsiao CD, Hwang PP*. The transcription factor,glial cell missing 2, is involved in differentiation and functional regulationof H+-ATPase-rich cells in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 296: R1192-1201.
2009. Tseng DY, Chou MY, Tseng YC, Hsiao CD, Huang CJ, Kaneko T, Hwang PP*. Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo. Am J Physiol Regul Integr Comp Physiol. 296: R549-557.
2008. Chou MY, Hsiao CD, Chen SC, Chen IW, Liu ST, Hwang PP*. Effects of hypothermia on gene expression in zebrafish gills: upregulation in differentiation andfunction of ionocytes as compensatory responses. J Exp Biol. 211: 3077-3084.
2008. Lin TY, Liao BK, Horng JL, Yan JJ, Hsiao CD, Hwang PP*. Carbonic anhydrase2-like a and 15a are involved in acid-base regulation and Na+ uptake inzebrafish H+-ATPase-rich cells. Am J Physiol Cell Physiol. 294: C1250-C1260.
2007. Hsiao CD, You MS, Guh YJ, Ma M, Jiang YJ, Hwang PP*. A Positive Regulatory Loop between foxi3aand foxi3b is Essential for Specification and Differentiation of the Zebrafish Epidermal Ionocytes. PLoS One 2:e302.
2006. Chen YC, Hsiao CD*, Lin WD, Hu CM, Hwang PP, Ho JM*. ZooDDD: an inter-species database for DDD analysis. Bioinformatics 22:2180-2182 [*Equal contribution]
2006. Lin WD*, Chen YC, Ho JM, Hsiao CD. GOBU: an integrative interface for manipulating biological objects. J Inf Sci Eng 22:19-29.
2006. Chu SL, Weng CF, Hsiao CD, Hwang PP, Chen YC, Ho JM, Lee SJ*. Profile analysis of expressed sequence tags derived from the ovary of tilapia, Oreochromis mossambicus. Aquaculture 251: 537-548.
2003. Hsiao CD, Ekker M, Tsai HJ*. Skin-specific expression of ictacalcin, a member of S100 genes, during zebrafish embryogenesis. Dev Dynamics 228:745-750.
2003. Hsiao CD, Tsai HJ*. Transgenic zebrafish with fluorescent germ cell: a useful tool to visualize germ cell proliferation and juvenile hermaphroditism in vivo. Dev Biol 262:313-323.
2003. Huang CJ, Tu CT, Hsiao CD, Hsieh FJ, Tsai HJ*. Germ-line transmission of myocardium-specific GFP transgene reveals critical regulatory elements in the cardiacmyosin light 2 promoter of zebrafish. Dev Dynamics 228:30-40.
2003. Hsiao CD, Tsai WY, Horng LS, Tsai HJ*. Molecular structure and developmental expression of three muscle-type troponin T genes in zebrafish. Dev Dynamics 227:266-279.
2002. Hsiao CD, Tsai WY, Tsai HJ*. Isolation and expression of two zebrafish homologues of parvalbumin genes related to chicken CPV3 and mammalian oncomodulin. Mech Dev 119S:S161-166.
2001. Hsiao CD, Hsieh FJ, Tsai HJ*. Enhanced expression and stable transmission of transgenes flanked by inverted terminal repeats from adeno-associated virus in zebrafish. Dev Dynamics 220:323-336.
Shih DF, Hsiao CD, Min MY, Lai SL, Yang CW, Lee WT*, Lee SJ*. Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor Functions. PLoS One. 8:e71741.
Lin DS*, Chiang MF, Ho CS, Hsiao CD, Lin CY, Wang NL, Chuang CK, Huang YW, Chang PC, Liu HL. Low-frequency enzyme replacement therapy in late-onset pompe disease. Muscle Nerve 47:612-613.
Hsiao CD*. Memorial Article on Chi-Bin Chien. Hereditas (Beijing), 35:519-521. (Invited review article)
2012
Chen CF, Chen CP, Hsiao CD*. Zebrafish research in Taiwan . Hereditas (Beijing). In press. (Invited review article)
Chu CY, Chen CF, Rajendran R. Samuel, Shen CN, Chen TH, Yen CC, Chuang CK, Lin DS, Hsiao CD*. Overexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafish. PLoS One. 7:e36474.
Chen YC, Chen YC, Lin WD, Hsiao CD, Chiu HW, Ho JM*. Bio301: a web-based EST annotation pipeline that facilitates functional comparison studies. ISRN Bioinformatics. 139842.
2011
Huang SH, Hsiao CD, Lin DS, Chow CY, Chang CJ, Liau I*. Imaging of Zebrafish In Vivo with Second-Harmonic Generation Reveals Shortened Sarcomeres Associated with Myopathy Induced by Statin. PLoS One. 6:e24764.
Lin YS, Tsai SC, Lin HC, Hsiao CD, Wu SM*. Changes of glycogen metabolism in the gills and hepatic tissue of tilapia (Oreochromis mossambicus) during short-term Cd exposure. Comp Biochem Physiol C Toxicol Pharmacol. 154:296-304.
Liu DW, Hsu CH,Tsai SM, Hsiao CD, Wang WP*. A Variant of Fibroblast Growth Factor Receptor 2 (Fgfr2) Regulates Left-Right Asymmetry in Zebrafish. PLoS One. 6:e21793.
Chen CF, Chu CY,Chen TH, Lee SJ, Shen CN, Hsiao CD*. Establishment of a transgenic zebrafish line for superficial skin ablation and functional validation of apoptosis modulators in vivo. PLoS One. 6:e20654.
Lin DS*, Hsiao CD, Liau I, Lin SP, Chiang MF, Chuang CK, Wang TJ, Wu TY, Jian YR, Huang SF, Liu HL. CNS-targeted AAV5 gene transfer results in global dispersal of vector and prevention of morphological and function deteriorationin CNS of globoid cell leukodystrophy mouse model. Mol Genet Metab. 103:367-377.
Yeh CM, Liu YC, Chang CJ, Lai SL, Hsiao CD, Lee SJ*. Ptenb mediatesgastrulation cell movements via Cdc42/AKT1 in zebrafish. PLoS One. 6:e18702.
Before 2009
2009. Chang WJ, HorngJL, Yan JJ, Hsiao CD, Hwang PP*. The transcription factor,glial cell missing 2, is involved in differentiation and functional regulationof H+-ATPase-rich cells in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 296: R1192-1201.
2009. Tseng DY, Chou MY, Tseng YC, Hsiao CD, Huang CJ, Kaneko T, Hwang PP*. Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo. Am J Physiol Regul Integr Comp Physiol. 296: R549-557.
2008. Chou MY, Hsiao CD, Chen SC, Chen IW, Liu ST, Hwang PP*. Effects of hypothermia on gene expression in zebrafish gills: upregulation in differentiation andfunction of ionocytes as compensatory responses. J Exp Biol. 211: 3077-3084.
2008. Lin TY, Liao BK, Horng JL, Yan JJ, Hsiao CD, Hwang PP*. Carbonic anhydrase2-like a and 15a are involved in acid-base regulation and Na+ uptake inzebrafish H+-ATPase-rich cells. Am J Physiol Cell Physiol. 294: C1250-C1260.
2007. Hsiao CD, You MS, Guh YJ, Ma M, Jiang YJ, Hwang PP*. A Positive Regulatory Loop between foxi3aand foxi3b is Essential for Specification and Differentiation of the Zebrafish Epidermal Ionocytes. PLoS One 2:e302.
2006. Chen YC, Hsiao CD*, Lin WD, Hu CM, Hwang PP, Ho JM*. ZooDDD: an inter-species database for DDD analysis. Bioinformatics 22:2180-2182 [*Equal contribution]
2006. Lin WD*, Chen YC, Ho JM, Hsiao CD. GOBU: an integrative interface for manipulating biological objects. J Inf Sci Eng 22:19-29.
2006. Chu SL, Weng CF, Hsiao CD, Hwang PP, Chen YC, Ho JM, Lee SJ*. Profile analysis of expressed sequence tags derived from the ovary of tilapia, Oreochromis mossambicus. Aquaculture 251: 537-548.
2003. Hsiao CD, Ekker M, Tsai HJ*. Skin-specific expression of ictacalcin, a member of S100 genes, during zebrafish embryogenesis. Dev Dynamics 228:745-750.
2003. Hsiao CD, Tsai HJ*. Transgenic zebrafish with fluorescent germ cell: a useful tool to visualize germ cell proliferation and juvenile hermaphroditism in vivo. Dev Biol 262:313-323.
2003. Huang CJ, Tu CT, Hsiao CD, Hsieh FJ, Tsai HJ*. Germ-line transmission of myocardium-specific GFP transgene reveals critical regulatory elements in the cardiacmyosin light 2 promoter of zebrafish. Dev Dynamics 228:30-40.
2003. Hsiao CD, Tsai WY, Horng LS, Tsai HJ*. Molecular structure and developmental expression of three muscle-type troponin T genes in zebrafish. Dev Dynamics 227:266-279.
2002. Hsiao CD, Tsai WY, Tsai HJ*. Isolation and expression of two zebrafish homologues of parvalbumin genes related to chicken CPV3 and mammalian oncomodulin. Mech Dev 119S:S161-166.
2001. Hsiao CD, Hsieh FJ, Tsai HJ*. Enhanced expression and stable transmission of transgenes flanked by inverted terminal repeats from adeno-associated virus in zebrafish. Dev Dynamics 220:323-336.